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Infectious mononucleosis is a viral disease caused by the Epstein-Barr virus that affects the reticuloendothelial system and has a broad spectrum of clinical presentations, ranging from non-symptomatic to severe. The patients usually develop transient IgM heterophile antibodies, have an abnormal increase in the amount of mononuclear leukocytes, and abnormal liver function. Disease diagnostic is obtained through the detection of heterophile antibodies (HE) or Paul-Burnell antibodies, or anti-viral structural antigens. The former generally decrease along the disease course, while the latter remain during the rest of his life.
A rapid slide test for the qualitative and semi-quantitative detection of heterophile antibodies specific for Infectious Mononucleosis (I.M.) in human serum.